Use of sensitivity discs as primary antibiotic standards in MIC determination.

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Use of sensitivity discs as primary antibiotic standards in MIC determination.

A method for the determination of minimum inhibitory concentration (MICs) is described, in which commercially prepared antibiotic sensitivity testing discs are used as primary antibiotic standards from which the necessary dilutions are prepared in WHO Perspex haemagglutination plates. The materials required are readily available in most laboratories at a cost in time and reagents that compares ...

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Antibiotic Sensitivity Discs

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Method of testing antibiotic sensitivity of spirochaetes, using antibiotic discs.

A rapid method of evaluating the susceptibility of spirochaetes to antibiotics would be convenient for investigators. Schneierson (1954) described a method of testing the susceptibility of strains of potentially pathogenic species, in which discs containing standard amounts of antibiotics were dropped into broth, and the broth was inoculated with the organism under study. He found that the resu...

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Comparison of tablets and paper discs for antibiotic sensitivity testing.

The value of tablets and paper discs as reservoirs of antimicrobial agents for use in sensitivity testing was compared. Antibiotics that were unstable in paper discs showed no demonstrable loss of activity in tablets over a period of 50 days under adverse storage conditions. The antibiotic content of commercially prepared tablets is very high in comparison with the accepted content of paper dis...

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ژورنال

عنوان ژورنال: Journal of Clinical Pathology

سال: 1978

ISSN: 0021-9746

DOI: 10.1136/jcp.31.9.855